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Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells

BACKGROUND: The objective of this study was to investigate the molecular mechanism by which miR-637 interferes with the expression of CDK6, which contributes to the development of pulmonary hypertension (PH) with chronic obstructive pulmonary disease (COPD). MATERIAL/METHODS: We used an online miRNA...

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Detalles Bibliográficos
Autores principales: Sang, Hai-yan, Jin, Ying-li, Zhang, Wen-qi, Chen, Li-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091202/
https://www.ncbi.nlm.nih.gov/pubmed/27794186
http://dx.doi.org/10.12659/MSM.897254