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Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells
BACKGROUND: The objective of this study was to investigate the molecular mechanism by which miR-637 interferes with the expression of CDK6, which contributes to the development of pulmonary hypertension (PH) with chronic obstructive pulmonary disease (COPD). MATERIAL/METHODS: We used an online miRNA...
Autores principales: | Sang, Hai-yan, Jin, Ying-li, Zhang, Wen-qi, Chen, Li-bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091202/ https://www.ncbi.nlm.nih.gov/pubmed/27794186 http://dx.doi.org/10.12659/MSM.897254 |
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