Cargando…

Molecular Mechanism of MicroRNA-200c Regulating Transforming Growth Factor-β (TGF-β)/SMAD Family Member 3 (SMAD3) Pathway by Targeting Zinc Finger E-Box Binding Homeobox 1 (ZEB1) in Hypospadias in Rats

BACKGROUND: The aim of this study was to explore effects of microRNA-200c regulating TGF-β/Smad3 pathway by targeting Zeb1 on the occurrence and development of hypospadias and to evaluate the relationship between microRNA-200c and occurrence of hypospadias. MATERIAL/METHODS: Pregnant rats with a ges...

Descripción completa

Detalles Bibliográficos
Autores principales: Qian, Chong, Dang, Xiangyang, Wang, Xianglin, Xu, Wei, Pang, Guijian, Chen, Yifeng, Liu, Chengbei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091215/
https://www.ncbi.nlm.nih.gov/pubmed/27794206
http://dx.doi.org/10.12659/MSM.896958