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Long-Term Alcohol-Induced Activation of Mammalian Target of Rapamycin is a Key Risk Factor of Epilepsy

BACKGROUND: The aim of this study was to determine whether activation of mammalian target of rapamycin (mTOR) is a key epileptogenic mechanism in the development of alcohol-related seizure. MATERIAL/METHODS: C57BL/6 mice were administered 10% ethanol in drinking water for 9 weeks. Video-electroencep...

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Detalles Bibliográficos
Autores principales: Fu, Xiaoling, Guo, Zhe, Gao, Chang, Chu, Qinying, Li, Jianhua, Ma, Hongying, Shu, Gangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091218/
https://www.ncbi.nlm.nih.gov/pubmed/27779177
http://dx.doi.org/10.12659/MSM.897018