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Ex vivo reversal of effects of rivaroxaban evaluated using thromboelastometry and thrombin generation assay

BACKGROUND: In major bleeding events, the new direct oral anticoagulants pose a great challenge for physicians. The aim of the study was to test for ex vivo reversal of the direct oral anticoagulant rivaroxaban with various non-specific reversal agents: prothrombin complex concentrate (PCC), activat...

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Detalles Bibliográficos
Autores principales: Schenk, B., Würtinger, P., Streif, W., Sturm, W., Fries, D., Bachler, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091332/
https://www.ncbi.nlm.nih.gov/pubmed/27623677
http://dx.doi.org/10.1093/bja/aew259