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Discovery of pan-VEGF inhibitory peptides directed to the extracellular ligand-binding domains of the VEGF receptors

Receptor tyrosine kinases (RTKs) are key molecules in numerous cellular processes, the inhibitors of which play an important role in the clinic. Among them are the vascular endothelial growth factor (VEGF) family members and their receptors (VEGFR), which are essential in the formation of new blood...

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Detalles Bibliográficos
Autores principales: Michaloski, Jussara S., Redondo, Alexandre R., Magalhães, Leila S., Cambui, Caio C., Giordano, Ricardo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091360/
https://www.ncbi.nlm.nih.gov/pubmed/27819042
http://dx.doi.org/10.1126/sciadv.1600611