Editor’s Highlight: Development of an In vitro Assay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety Assessment

A toxicity pathway approach was taken to develop an in vitro assay using human uterine epithelial adenocarcinoma (Ishikawa) cells as a replacement for measuring an in vivo uterotrophic response to estrogens. The Ishikawa cell was determined to be fit for the purpose of recapitulating in vivo uterine...

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Detalles Bibliográficos
Autores principales: Miller, Michelle M., Alyea, Rebecca A., LeSommer, Caroline, Doheny, Daniel L., Rowley, Sean M., Childs, Kristin M., Balbuena, Pergentino, Ross, Susan M., Dong, Jian, Sun, Bin, Andersen, Melvin A., Clewell, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
In vitro Assay for Uterine-Specific Actions of Estrogen-Like Compounds
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091368/
https://www.ncbi.nlm.nih.gov/pubmed/27503385
http://dx.doi.org/10.1093/toxsci/kfw152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091368/
https://www.ncbi.nlm.nih.gov/pubmed/27503385
http://dx.doi.org/10.1093/toxsci/kfw152

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