Cargando…

Editor’s Highlight: Development of an In vitro Assay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety Assessment

A toxicity pathway approach was taken to develop an in vitro assay using human uterine epithelial adenocarcinoma (Ishikawa) cells as a replacement for measuring an in vivo uterotrophic response to estrogens. The Ishikawa cell was determined to be fit for the purpose of recapitulating in vivo uterine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miller, Michelle M., Alyea, Rebecca A., LeSommer, Caroline, Doheny, Daniel L., Rowley, Sean M., Childs, Kristin M., Balbuena, Pergentino, Ross, Susan M., Dong, Jian, Sun, Bin, Andersen, Melvin A., Clewell, Rebecca A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	In vitro Assay for Uterine-Specific Actions of Estrogen-Like Compounds
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091368/ https://www.ncbi.nlm.nih.gov/pubmed/27503385 http://dx.doi.org/10.1093/toxsci/kfw152

Ejemplares similares

Session Summary: Nontraditional Sites of Estrogen Action
por: Metzger, Deborah A.
Publicado: (1995)

A case of subconjunctival dirofilariasis in South India
por: Bhat, Savita, et al.
Publicado: (2012)

Endometrial Cancers Harboring Mutated Fibroblast Growth Factor Receptor 2 Protein Are Successfully Treated With a New Small Tyrosine Kinase Inhibitor in an Orthotopic Mouse Model
por: Taurin, Sebastien, et al.
Publicado: (2018)

Preoperative Tumor Size at MRI Predicts Deep Myometrial Invasion, Lymph Node Metastases, and Patient Outcome in Endometrial Carcinomas
por: Ytre-Hauge, Sigmund, et al.
Publicado: (2015)

Diffuse infiltrative syphilitic retinitis in an HIV-positive patient
por: Rahman, Hassan Toufiqur, et al.
Publicado: (2011)

A case of bilateral Chikungunya neuroretinitis
por: Nair, Akshay Gopinathan, et al.
Publicado: (2011)

Healing patterns of choroidal tubercles after antitubercular therapy: A photographic and OCT study
por: Mehta, Salil
Publicado: (2011)

Subretinal pigment epithelial infiltrates in primary vitreoretinal lymphoma
por: Vasconcelos-Santos, Daniel Vítor, et al.
Publicado: (2011)

Pharmacological correction of misfolding of ABC proteins()
por: Rudashevskaya, Elena L., et al.
Publicado: (2014)

Women’s Sleep Disorders: Integrative Care
por: Frange, Cristina, et al.
Publicado: (2017)

Efficacy and Safety of AEZS-108 (LHRH Agonist Linked to Doxorubicin) in Women With Advanced or Recurrent Endometrial Cancer Expressing LHRH Receptors: A Multicenter Phase 2 Trial (AGO-GYN5)
por: Emons, Günter, et al.
Publicado: (2014)

Increased Association Between Endometriosis and Endometrial Cancer: A Nationwide Population-Based Retrospective Cohort Study
por: Yu, Hann-Chin, et al.
Publicado: (2015)

Prior Tubal Ligation Might Influence Metastatic Spread of Nonendometrioid Endometrial Carcinoma
por: Li, Mingxia, et al.
Publicado: (2016)

Should the Optimal Adjuvant Treatment for Patients With Early-Stage Endometrial Cancer With High-Intermediate Risk Factors Depend on Tumor Grade?
por: Lan, Chunyan, et al.
Publicado: (2015)

Comparison of Survival Benefits of Combined Chemotherapy and Radiotherapy Versus Chemotherapy Alone for Uterine Serous Carcinoma: A Meta-analysis
por: Lin, Yanying, et al.
Publicado: (2017)

Fertility Preserved Hysteroscopic Approach for the Treatment of Stage Ia Endometrioid Carcinoma
por: Wang, Fangfang, et al.
Publicado: (2017)

The Use of Endometrial Cancer Patient–Derived Organoid Culture for Drug Sensitivity Testing Is Feasible
por: Girda, Eugenia, et al.
Publicado: (2017)

Possible Risk Factors of Pulmonary Metastases in Patients With International Federation of Gynecology and Obstetrics Stage I Endometrioid-Type Endometrial Cancer
por: Jiang, Wei, et al.
Publicado: (2017)

“Metalloestrogenic” effects of cadmium downstream of G protein-coupled estrogen receptor and mitogen-activated protein kinase pathways in human uterine fibroid cells
por: Yu, Linda, et al.
Publicado: (2021)

Editor’s Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells
por: Mesnage, Robin, et al.
Publicado: (2017)

A comparison of thyroidal protection by iodine and perchlorate against radioiodine exposure in Caucasians and Japanese
por: Rump, A., et al.
Publicado: (2021)

A comparison of the chemo- and radiotoxicity of thorium and uranium at different enrichment grades
por: Rump, A., et al.
Publicado: (2023)

A newly designed real-time RT-PCR for SAFV detects SAFV-2 and SAFV-3 in the respiratory tracts of ill children during 2011
por: Wang, C.Y.T., et al.
Publicado: (2012)

Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements
por: Weinmuellner, R., et al.
Publicado: (2017)

1,1′-Dimethoxy-3,3′-dimethyl-3,3′-(hexane-1,6-diyl)bis(triazen-2-ium-2-olate): a nitric oxide donor
por: Zhou, Zhengrong, et al.
Publicado: (2009)

Synthesis of Co(II) and Ni(II) Asymmetric Tetraazamacrocyclic Complexes and Their Electrochemical and Antimicrobial Studies
por: Vashistha, V. K., et al.
Publicado: (2021)

Chronic exposure to inorganic arsenic and fluoride induces redox imbalance, inhibits the transsulfuration pathway, and alters glutamate receptor expression in the brain, resulting in memory impairment in adult male mouse offspring
por: González-Alfonso, Wendy L., et al.
Publicado: (2023)

Genotoxicity and inflammatory potential of stainless steel welding fume particles: an in vitro study on standard vs Cr(VI)-reduced flux-cored wires and the role of released metals
por: McCarrick, Sarah, et al.
Publicado: (2021)

Cu(II)(PhOMe-Salophen) Complex: Greener Pasture Biological Study, XRD/HAS Interactions, and MEP
por: Manas Bandyopadhyay, et al.
Publicado: (2023)

Oxidatively damaged guanosine in white blood cells and in urine of welders: associations with exposure to welding fumes and body iron stores
por: Pesch, Beate, et al.
Publicado: (2014)

Accurate stereochemistry for two related 22,26-epiminocholestene derivatives
por: Vega-Baez, José Luis, et al.
Publicado: (2008)

N-{N-[2-(3,5-Difluorophenyl)acetyl]-(S)-alanyl}-(S)-phenylglycine tert-butyl ester (DAPT): an inhibitor of γ-secretase, revealing fine electronic and hydrogen-bonding features
por: Czerwinski, Andrzej, et al.
Publicado: (2010)

Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo
por: Zhu, Jia-Qiao, et al.
Publicado: (2013)

Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles
por: Xu, Jiegou, et al.
Publicado: (2013)

Interactions of silica nanoparticles with lung epithelial cells and the association to flotillins
por: Kasper, Jennifer, et al.
Publicado: (2012)

Prenatal arsenic exposure is associated with increased plasma IGFBP3 concentrations in 9-year-old children partly via changes in DNA methylation
por: Gliga, Anda R., et al.
Publicado: (2018)

Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women
por: Engström, Karin, et al.
Publicado: (2016)

Cytotoxicity of fractured quartz on THP-1 human macrophages: role of the membranolytic activity of quartz and phagolysosome destabilization
por: Leinardi, Riccardo, et al.
Publicado: (2020)

Long-term simulation of lead concentrations in agricultural soils in relation to human adverse health effects
por: Schupp, Thomas, et al.
Publicado: (2020)

Role of microRNAs in response to cadmium chloride in pancreatic ductal adenocarcinoma
por: Mortoglou, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9m6mnudel59cmqsclfakgm3tja