Partially Saturated Bicyclic Heteroaromatics as an sp(3)‐Enriched Fragment Collection

Fragment‐based lead generation has proven to be an effective means of identifying high‐quality lead compounds for drug discovery programs. However, the fragment screening sets often used are principally comprised of sp(2)‐rich aromatic compounds, which limits the structural (and hence biological) di...

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Detalles Bibliográficos
Autores principales: Twigg, David G., Kondo, Noriyasu, Mitchell, Sophie L., Galloway, Warren R. J. D., Sore, Hannah F., Madin, Andrew, Spring, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091628/
https://www.ncbi.nlm.nih.gov/pubmed/27596095
http://dx.doi.org/10.1002/anie.201606496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091628/
https://www.ncbi.nlm.nih.gov/pubmed/27596095
http://dx.doi.org/10.1002/anie.201606496

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