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Partially Saturated Bicyclic Heteroaromatics as an sp(3)‐Enriched Fragment Collection
Fragment‐based lead generation has proven to be an effective means of identifying high‐quality lead compounds for drug discovery programs. However, the fragment screening sets often used are principally comprised of sp(2)‐rich aromatic compounds, which limits the structural (and hence biological) di...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091628/ https://www.ncbi.nlm.nih.gov/pubmed/27596095 http://dx.doi.org/10.1002/anie.201606496 |