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Using HHsearch to tackle proteins of unknown function: A pilot study with PH domains
Advances in membrane cell biology are hampered by the relatively high proportion of proteins with no known function. Such proteins are largely or entirely devoid of structurally significant domain annotations. Structural bioinformaticians have developed profile‐profile tools such as HHsearch (online...
Autores principales: | Fidler, David R., Murphy, Sarah E., Courtis, Katherine, Antonoudiou, Pantelis, El‐Tohamy, Rana, Ient, Jonathan, Levine, Timothy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons A/S
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091641/ https://www.ncbi.nlm.nih.gov/pubmed/27601190 http://dx.doi.org/10.1111/tra.12432 |
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