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Serum Insulin Levels Are Reduced by Intravenous Ghrelin Administration but Do Not Correlate with Alcohol Craving in Alcohol-Dependent Individuals

BACKGROUND: Increasing evidence supports a role for appetite-regulating pathways like ghrelin, insulin, and leptin in alcoholism. We previously reported that intravenous (i.v.) exogenous ghrelin increases alcohol craving. We also reported i.v. ghrelin reduces endogenous serum leptin, whose levels, i...

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Detalles Bibliográficos
Autores principales: Haass-Koffler, Carolina L., Giovenco, Danielle E., Lee, Mary R., Zywiak, William H., de la Monte, Suzanne M., Kenna, George A., Swift, Robert M., Leggio, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091823/
https://www.ncbi.nlm.nih.gov/pubmed/27207912
http://dx.doi.org/10.1093/ijnp/pyw048