EGF-Induced VEGF Exerts a PI3K-Dependent Positive Feedback on ERK and AKT through VEGFR2 in Hematological In Vitro Models

EGFR and VEGFR pathways play major roles in solid tumor growth and progression, however, little is known about these pathways in haematological tumors. This study investigated the crosstalk between EGFR and VEGFR2 signaling in two hematological in vitro models: THP1, a human monocytic leukemia, and...

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Detalles Bibliográficos
Autores principales: Saryeddine, Lilian, Zibara, Kazem, Kassem, Nouhad, Badran, Bassam, El-Zein, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091849/
https://www.ncbi.nlm.nih.gov/pubmed/27806094
http://dx.doi.org/10.1371/journal.pone.0165876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091849/
https://www.ncbi.nlm.nih.gov/pubmed/27806094
http://dx.doi.org/10.1371/journal.pone.0165876

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