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Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps

Decline in hippocampal-dependent explicit memory (memory for facts and events) is one of the earliest clinical symptom of Alzheimer's disease (AD). It is well established that synapse loss and ensuing neurodegeneration are the best predictors for memory impairments in AD. Latest studies have em...

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Detalles Bibliográficos
Autores principales: Sajadi, Ahmadali, Provost, Chloé, Pham, Brendon, Brouillette, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091865/
https://www.ncbi.nlm.nih.gov/pubmed/27585306
http://dx.doi.org/10.3791/54215