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Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia

Giardiasis is widely acknowledged to be a neglected disease in need of new therapeutics to address toxicity and resistance issues associated with the limited available treatment options. We examined seven protein kinases in the Giardia lamblia genome that are predicted to share an unusual structural...

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Detalles Bibliográficos
Autores principales: Hennessey, Kelly M., Smith, Tess R., Xu, Jennifer W., Alas, Germain C. M., Ojo, Kayode K., Merritt, Ethan A., Paredez, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091913/
https://www.ncbi.nlm.nih.gov/pubmed/27806042
http://dx.doi.org/10.1371/journal.pntd.0005107