Inhibiting Extracellular Vesicle Release from Human Cardiosphere Derived Cells with Lentiviral Knockdown of nSMase2 Differentially Effects Proliferation and Apoptosis in Cardiomyocytes, Fibroblasts and Endothelial Cells In Vitro

Numerous studies have shown a beneficial effect of cardiosphere-derived cell (CDC) therapy on regeneration of injured myocardium. Paracrine signaling by CDC secreted exosomes may contribute to improved cardiac function. However, it has not yet been demonstrated by a genetic approach that exosome rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Lang, Jennifer K., Young, Rebeccah F., Ashraf, Hashmat, Canty, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091915/
https://www.ncbi.nlm.nih.gov/pubmed/27806113
http://dx.doi.org/10.1371/journal.pone.0165926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091915/
https://www.ncbi.nlm.nih.gov/pubmed/27806113
http://dx.doi.org/10.1371/journal.pone.0165926

Ejemplares similares