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Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

A major hallmark of the autoimmune demyelinating disease multiple sclerosis (MS) is immune cell infiltration into the brain and spinal cord resulting in myelin destruction, which not only slows conduction of nerve impulses, but causes axonal injury resulting in motor and cognitive decline. Current t...

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Detalles Bibliográficos
Autores principales: Evonuk, Kirsten S., Moseley, Carson E., Doyle, Ryan E., Weaver, Casey T., DeSilva, Tara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092010/
https://www.ncbi.nlm.nih.gov/pubmed/27685467
http://dx.doi.org/10.3791/54348