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Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons

Evolutionary differences in gene regulation between humans and lower mammalian experimental systems are incompletely understood, a potential translational obstacle that is challenging to surmount in neurons, where primary tissue availability is poor. Rodent-based studies show that activity-dependent...

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Detalles Bibliográficos
Autores principales: Qiu, Jing, McQueen, Jamie, Bilican, Bilada, Dando, Owen, Magnani, Dario, Punovuori, Karolina, Selvaraj, Bhuvaneish T, Livesey, Matthew, Haghi, Ghazal, Heron, Samuel, Burr, Karen, Patani, Rickie, Rajan, Rinku, Sheppard, Olivia, Kind, Peter C, Simpson, T Ian, Tybulewicz, Victor LJ, Wyllie, David JA, Fisher, Elizabeth MC, Lowell, Sally, Chandran, Siddharthan, Hardingham, Giles E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092045/
https://www.ncbi.nlm.nih.gov/pubmed/27692071
http://dx.doi.org/10.7554/eLife.20337