Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Membrane proteins (MPs) are essential components of cellular membranes and primary drug targets. Rational drug design relies on precise structural information, typically obtained by crystallography; however MPs are difficult to crystallize. Recent progress in MP structural determination has benefite...

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Detalles Bibliográficos
Autores principales: Ishchenko, Andrii, Cherezov, Vadim, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092055/
https://www.ncbi.nlm.nih.gov/pubmed/27683972
http://dx.doi.org/10.3791/54463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092055/
https://www.ncbi.nlm.nih.gov/pubmed/27683972
http://dx.doi.org/10.3791/54463

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