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Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
BACKGROUND: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The default method in GeneChip expression microarray uses a constant factor, the scaling factor (SF), for every gene on an array....
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509236/ https://www.ncbi.nlm.nih.gov/pubmed/15283861 http://dx.doi.org/10.1186/1471-2105-5-103 |