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Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays

BACKGROUND: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The default method in GeneChip expression microarray uses a constant factor, the scaling factor (SF), for every gene on an array....

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Detalles Bibliográficos
Autor principal: Lu, Chao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509236/
https://www.ncbi.nlm.nih.gov/pubmed/15283861
http://dx.doi.org/10.1186/1471-2105-5-103