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MUS81-EME2 Promotes Replication Fork Restart

Replication forks frequently stall at regions of the genome that are difficult to replicate or contain lesions that cause replication blockage. An important mechanism for the restart of a stalled fork involves endonucleolytic cleavage that can lead to fork restoration and replication progression. He...

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Detalles Bibliográficos
Autores principales: Pepe, Alessandra, West, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092538/
https://www.ncbi.nlm.nih.gov/pubmed/24813886
http://dx.doi.org/10.1016/j.celrep.2014.04.007