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Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report an analysis of 3,127 integration site sequences from human cells. We compared retroviral vectors derived from human immunodeficiency virus (HIV), avian sarcoma-leukosis vir...

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Detalles Bibliográficos
Autores principales: Mitchell, Rick S, Beitzel, Brett F, Schroder, Astrid R. W, Shinn, Paul, Chen, Huaming, Berry, Charles C, Ecker, Joseph R, Bushman, Frederic D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509299/
https://www.ncbi.nlm.nih.gov/pubmed/15314653
http://dx.doi.org/10.1371/journal.pbio.0020234