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Gcn4p and Novel Upstream Activating Sequences Regulate Targets of the Unfolded Protein Response
Eukaryotic cells respond to accumulation of unfolded proteins in the endoplasmic reticulum (ER) by activating the unfolded protein response (UPR), a signal transduction pathway that communicates between the ER and the nucleus. In yeast, a large set of UPR target genes has been experimentally determi...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509306/ https://www.ncbi.nlm.nih.gov/pubmed/15314660 http://dx.doi.org/10.1371/journal.pbio.0020246 |