The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells

Bcl-3 is an atypical member of the IκB family. It associates with p50/NF-κB1 and p52/NF-κB2 homodimers in nuclei where it modulates transcription in a context-dependent manner. A subset of B cell tumors exhibits recurrent translocations of Bcl-3, resulting in overexpression. Elevated expression with...

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Detalles Bibliográficos
Autores principales: Tang, Wanhu, Wang, Hongshan, Ha, Hye-lin, Tassi, Ilaria, Bhardwaj, Reetika, Claudio, Estefania, Siebenlist, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093091/
https://www.ncbi.nlm.nih.gov/pubmed/27132515
http://dx.doi.org/10.1038/onc.2016.152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093091/
https://www.ncbi.nlm.nih.gov/pubmed/27132515
http://dx.doi.org/10.1038/onc.2016.152

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