Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma

Axonal transport deficits precede structural loss in glaucoma and other neurodegenerations. Impairments in structural support, including modified cytoskeletal proteins, and microtubule-destabilizing elements, could be initiating factors in glaucoma pathogenesis. We investigated the time course of ch...

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Detalles Bibliográficos
Autores principales: Wilson, Gina N., Smith, Matthew A., Inman, Denise M., Dengler-Crish, Christine M., Crish, Samuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093131/
https://www.ncbi.nlm.nih.gov/pubmed/27857681
http://dx.doi.org/10.3389/fnins.2016.00494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093131/
https://www.ncbi.nlm.nih.gov/pubmed/27857681
http://dx.doi.org/10.3389/fnins.2016.00494

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