Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality

Although two in vitro cultivation methods have been reported, discrimination of infectious human norovirus particles for study of viral inactivation is still a challenge, as both rely on reverse transcriptase quantitative PCR. Histo-blood group antigen (HBGA) binding assays serve as a proxy for esti...

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Detalles Bibliográficos
Autores principales: Moore, Matthew D., Bobay, Benjamin G., Mertens, Brittany, Jaykus, Lee-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093151/
https://www.ncbi.nlm.nih.gov/pubmed/27830193
http://dx.doi.org/10.1128/mSphere.00298-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093151/
https://www.ncbi.nlm.nih.gov/pubmed/27830193
http://dx.doi.org/10.1128/mSphere.00298-16

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