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BCR and chemokine responses upon anti-IgM and anti-IgD stimulation in chronic lymphocytic leukaemia
Dysregulation of B cell receptor (BCR) signalling is a hallmark of chronic lymphocytic leukaemia (CLL) pathology, and targeting BCR pathway kinases has brought great therapeutic advances. Activation of the BCR in lymphoid organs has been associated with CLL cell proliferation and survival, leading t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093209/ https://www.ncbi.nlm.nih.gov/pubmed/27542958 http://dx.doi.org/10.1007/s00277-016-2788-6 |