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BCR and chemokine responses upon anti-IgM and anti-IgD stimulation in chronic lymphocytic leukaemia

Dysregulation of B cell receptor (BCR) signalling is a hallmark of chronic lymphocytic leukaemia (CLL) pathology, and targeting BCR pathway kinases has brought great therapeutic advances. Activation of the BCR in lymphoid organs has been associated with CLL cell proliferation and survival, leading t...

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Detalles Bibliográficos
Autores principales: Haerzschel, Andrea, Catusse, Julie, Hutterer, Evelyn, Paunovic, Manuela, Zirlik, Katja, Eibel, Hermann, Krenn, Peter W., Hartmann, Tanja N., Burger, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093209/
https://www.ncbi.nlm.nih.gov/pubmed/27542958
http://dx.doi.org/10.1007/s00277-016-2788-6