Computational Analysis of Damaging Single-Nucleotide Polymorphisms and Their Structural and Functional Impact on the Insulin Receptor

Single-nucleotide polymorphisms (SNPs) associated with complex disorders can create, destroy, or modify protein coding sites. Single amino acid substitutions in the insulin receptor (INSR) are the most common forms of genetic variations that account for various diseases like Donohue syndrome or Lepr...

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Detalles Bibliográficos
Autores principales: Mahmud, Zabed, Malik, Syeda Umme Fahmida, Ahmed, Jahed, Azad, Abul Kalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093252/
https://www.ncbi.nlm.nih.gov/pubmed/27840822
http://dx.doi.org/10.1155/2016/2023803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093252/
https://www.ncbi.nlm.nih.gov/pubmed/27840822
http://dx.doi.org/10.1155/2016/2023803

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