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Sulfated hyaluronan alters fibronectin matrix assembly and promotes osteogenic differentiation of human bone marrow stromal cells

Extracellular matrix (ECM) composition and structural integrity is one of many factors that influence cellular differentiation. Fibronectin (FN) which is in many tissues the most abundant ECM protein forms a unique fibrillary network. FN homes several binding sites for sulfated glycosaminoglycans (s...

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Detalles Bibliográficos
Autores principales: Vogel, Sarah, Arnoldini, Simon, Möller, Stephanie, Schnabelrauch, Matthias, Hempel, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093463/
https://www.ncbi.nlm.nih.gov/pubmed/27808176
http://dx.doi.org/10.1038/srep36418