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Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions

Candida albicans is a common cause of life-threatening fungal bloodstream infections. In the murine model of systemic candidiasis, the kidney is the primary target organ while the fungal load declines over time in liver and spleen. To better understand these organ-specific differences in host-pathog...

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Detalles Bibliográficos
Autores principales: Hebecker, Betty, Vlaic, Sebastian, Conrad, Theresia, Bauer, Michael, Brunke, Sascha, Kapitan, Mario, Linde, Jörg, Hube, Bernhard, Jacobsen, Ilse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093689/
https://www.ncbi.nlm.nih.gov/pubmed/27808111
http://dx.doi.org/10.1038/srep36055