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Metal-coupled folding as the driving force for the extreme stability of Rad50 zinc hook dimer assembly
The binding of metal ions at the interface of protein complexes presents a unique and poorly understood mechanism of molecular assembly. A remarkable example is the Rad50 zinc hook domain, which is highly conserved and facilitates the Zn(2+)-mediated homodimerization of Rad50 proteins. Here, we pres...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093744/ https://www.ncbi.nlm.nih.gov/pubmed/27808280 http://dx.doi.org/10.1038/srep36346 |