Improving virus production through quasispecies genomic selection and molecular breeding

Virus production still is a challenging issue in antigen manufacture, particularly with slow-growing viruses. Deep-sequencing of genomic regions indicative of efficient replication may be used to identify high-fitness minority individuals suppressed by the ensemble of mutants in a virus quasispecies...

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Detalles Bibliográficos
Autores principales: Pérez-Rodríguez, Francisco J., D’Andrea, Lucía, de Castellarnau, Montserrat, Costafreda, Maria Isabel, Guix, Susana, Ribes, Enric, Quer, Josep, Gregori, Josep, Bosch, Albert, Pintó, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093897/
https://www.ncbi.nlm.nih.gov/pubmed/27808108
http://dx.doi.org/10.1038/srep35962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093897/
https://www.ncbi.nlm.nih.gov/pubmed/27808108
http://dx.doi.org/10.1038/srep35962

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