Cargando…

The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease

The presence of only small amounts of misfolded protein is an indication of a healthy proteome. Maintaining proteome health, or more specifically, “proteostasis,” is the purview of the “proteostasis network.” This network must respond to constant fluctuations in the amount of destabilized proteins c...

Descripción completa

Detalles Bibliográficos
Autor principal: Kikis, Elise A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093949/
https://www.ncbi.nlm.nih.gov/pubmed/27809888
http://dx.doi.org/10.1186/s13062-016-0161-2