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The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease
The presence of only small amounts of misfolded protein is an indication of a healthy proteome. Maintaining proteome health, or more specifically, “proteostasis,” is the purview of the “proteostasis network.” This network must respond to constant fluctuations in the amount of destabilized proteins c...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093949/ https://www.ncbi.nlm.nih.gov/pubmed/27809888 http://dx.doi.org/10.1186/s13062-016-0161-2 |