MIR137 is the key gene mediator of the syndromic obesity phenotype of patients with 1p21.3 microdeletions

BACKGROUND: Deletions in the long arm of chromosome 1 have been described in patients with a phenotype consisting primarily of obesity, intellectual disability and autism-spectrum disorder. The minimal region of overlap comprises two genes: DPYD and MIR137. CASE PRESENTATION: We describe a 10-year-o...

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Detalles Bibliográficos
Autores principales: Tucci, Arianna, Ciaccio, Claudia, Scuvera, Giulietta, Esposito, Susanna, Milani, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093957/
https://www.ncbi.nlm.nih.gov/pubmed/27822311
http://dx.doi.org/10.1186/s13039-016-0289-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093957/
https://www.ncbi.nlm.nih.gov/pubmed/27822311
http://dx.doi.org/10.1186/s13039-016-0289-x

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