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MIR137 is the key gene mediator of the syndromic obesity phenotype of patients with 1p21.3 microdeletions
BACKGROUND: Deletions in the long arm of chromosome 1 have been described in patients with a phenotype consisting primarily of obesity, intellectual disability and autism-spectrum disorder. The minimal region of overlap comprises two genes: DPYD and MIR137. CASE PRESENTATION: We describe a 10-year-o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093957/ https://www.ncbi.nlm.nih.gov/pubmed/27822311 http://dx.doi.org/10.1186/s13039-016-0289-x |