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Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs

BACKGROUND: Malaria parasites of the genus Plasmodium possess large hyper-variable families of antigen-encoding genes. These are often variantly-expressed and are major virulence factors for immune evasion and the maintenance of chronic infections. Recombination and diversification of these gene fam...

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Detalles Bibliográficos
Autores principales: Stanton, Adam, Harris, Lynne M., Graham, Gemma, Merrick, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093961/
https://www.ncbi.nlm.nih.gov/pubmed/27809775
http://dx.doi.org/10.1186/s12864-016-3183-3