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Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs
BACKGROUND: Malaria parasites of the genus Plasmodium possess large hyper-variable families of antigen-encoding genes. These are often variantly-expressed and are major virulence factors for immune evasion and the maintenance of chronic infections. Recombination and diversification of these gene fam...
Autores principales: | Stanton, Adam, Harris, Lynne M., Graham, Gemma, Merrick, Catherine J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093961/ https://www.ncbi.nlm.nih.gov/pubmed/27809775 http://dx.doi.org/10.1186/s12864-016-3183-3 |
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