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Emerin Caps the Pointed End of Actin Filaments: Evidence for an Actin Cortical Network at the Nuclear Inner Membrane
X-linked Emery-Dreifuss muscular dystrophy is caused by loss of emerin, a LEM-domain protein of the nuclear inner membrane. To better understand emerin function, we used affinity chromatography to purify emerin-binding proteins from nuclear extracts of HeLa cells. Complexes that included actin, αII-...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509406/ https://www.ncbi.nlm.nih.gov/pubmed/15328537 http://dx.doi.org/10.1371/journal.pbio.0020231 |