Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus

BACKGROUND: Vascular disease in diabetes is initiated by monocyte adhesion to vascular endothelium, transmigration and formation of foam cells. Increasing clinical evidence supports a role for the secretory protein, cyclophilin A in diabetic vascular disease. The means by which cyclophilin A contrib...

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Detalles Bibliográficos
Autores principales: Ramachandran, Surya, Vinitha, Anandan, Kartha, Cheranellore Chandrasekharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094075/
https://www.ncbi.nlm.nih.gov/pubmed/27809851
http://dx.doi.org/10.1186/s12933-016-0467-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094075/
https://www.ncbi.nlm.nih.gov/pubmed/27809851
http://dx.doi.org/10.1186/s12933-016-0467-5

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