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Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology

BACKGROUND: Human papillomaviruses (HPVs) are a worldwide burden as they are a widespread group of tumour viruses in humans. Having a tropism for mucosal tissues, high-risk HPVs are detected in nearly all cervical cancers. HPV16 is the most common high-risk type but not all women infected with high-...

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Detalles Bibliográficos
Autores principales: Jackson, Robert, Rosa, Bruce A., Lameiras, Sonia, Cuninghame, Sean, Bernard, Josee, Floriano, Wely B., Lambert, Paul F., Nicolas, Alain, Zehbe, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094076/
https://www.ncbi.nlm.nih.gov/pubmed/27806689
http://dx.doi.org/10.1186/s12864-016-3203-3