Nucleophosmin mutation analysis in acute myeloid leukaemia: Immunohistochemistry as a surrogate for molecular techniques

BACKGROUND & OBJECTIVES: Mutation of nucleophosmin (NPM1) gene in the absence of FLT3-ITD (FMS related tyrosine kinase 3 - internal tandem duplications) mutation carries a good prognosis in cytogenetically normal acute myeloid leukaemia (AML). NPM1, a multifunctional nucleolar phosphoprotein tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Chopra, Anita, Soni, Sushant, Pati, Haraprasad, Kumar, Dev, Diwedi, Rahul, Verma, Deepak, Vishwakama, Garima, Bakhshi, Sameer, Kumar, Suman, Gogia, Ajay, Kumar, Rajive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094116/
https://www.ncbi.nlm.nih.gov/pubmed/27748301
http://dx.doi.org/10.4103/0971-5916.192027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094116/
https://www.ncbi.nlm.nih.gov/pubmed/27748301
http://dx.doi.org/10.4103/0971-5916.192027

Ejemplares similares