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Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis

Sepsis is commonly associated with brain dysfunction, but the underlying mechanisms remain unclear, although mitochondrial dysfunction and microvascular abnormalities have been implicated. We therefore assessed whether cerebral mitochondrial dysfunction during systemic endotoxemia in mice increased...

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Detalles Bibliográficos
Autores principales: Chisholm, Kim I, Ida, Keila K, Davies, Andrew L, Tachtsidis, Ilias, Papkovsky, Dmitri B, Dyson, Alex, Singer, Mervyn, Duchen, Michael R, Smith, Kenneth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094296/
https://www.ncbi.nlm.nih.gov/pubmed/26661160
http://dx.doi.org/10.1177/0271678X15606457