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Oxalomalate reduces expression and secretion of vascular endothelial growth factor in the retinal pigment epithelium and inhibits angiogenesis: Implications for age-related macular degeneration

Clinical and experimental observations indicate a critical role for vascular endothelial growth factor (VEGF), secreted by the retinal pigment epithelium (RPE), in pathological angiogenesis and the development of choroidal neovascularization (CNV) in age-related macular degeneration (AMD). RPE-media...

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Detalles Bibliográficos
Autores principales: Kim, Sung Hwan, Kim, Hyunjin, Ku, Hyeong Jun, Park, Jung Hyun, Cha, Hanvit, Lee, Seoyoon, Lee, Jin Hyup, Park, Jeen-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094379/
https://www.ncbi.nlm.nih.gov/pubmed/27810736
http://dx.doi.org/10.1016/j.redox.2016.10.008