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Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties
Calreticulin (CRT) is a multifaceted protein, initially discovered as an endoplasmic reticulum (ER) chaperone protein, that is essential in calcium metabolism. Various implications in cancer, early development and immunology have been discovered more recently for CRT, as well as its role as a domina...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094443/ https://www.ncbi.nlm.nih.gov/pubmed/27840680 http://dx.doi.org/10.1107/S2052252516012847 |