Molecular modeling, synthesis, characterization and pharmacological evaluation of benzo[d]oxazole derivatives as non-steroidal anti-inflammatory agents

A series of N-(2-(4-chlorobenzyl)benzo[d]oxazol-5-yl)-3-substituted-propanamide (3a–3n) were synthesized and evaluated for their acute and chronic anti-inflammatory potential. The structure of the compounds was elucidated by elemental and spectral (IR, (1)H NMR and MS) analysis. The synthesized comp...

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Detalles Bibliográficos
Autores principales: Shakya, Ashok K., Kaur, Avneet, Al-Najjar, Belal O., Naik, Rajashri R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094471/
https://www.ncbi.nlm.nih.gov/pubmed/27829803
http://dx.doi.org/10.1016/j.jsps.2015.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094471/
https://www.ncbi.nlm.nih.gov/pubmed/27829803
http://dx.doi.org/10.1016/j.jsps.2015.03.018

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