Peripheral neuropathy via mutant tRNA synthetases: Inhibition of protein translation provides a possible explanation

Recent evidence indicates that inhibition of protein translation may be a common pathogenic mechanism for peripheral neuropathy associated with mutant tRNA synthetases (aaRSs). aaRSs are enzymes that ligate amino acids to their cognate tRNA, thus catalyzing the first step of translation. Dominant mu...

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Detalles Bibliográficos
Autor principal: Storkebaum, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Insights & Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094542/
https://www.ncbi.nlm.nih.gov/pubmed/27352040
http://dx.doi.org/10.1002/bies.201600052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094542/
https://www.ncbi.nlm.nih.gov/pubmed/27352040
http://dx.doi.org/10.1002/bies.201600052

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