Sterically Demanding Oxidative Amidation of α‐Substituted Malononitriles with Amines Using O(2)

An efficient amidation method between readily available 1,1‐dicyanoalkanes and either chiral or nonchiral amines was realized simply with molecular oxygen and a carbonate base. This oxidative protocol can be applied to both sterically and electronically challenging substrates in a highly chemoselect...

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Detalles Bibliográficos
Autores principales: Li, Jing, Lear, Martin J., Hayashi, Yujiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094546/
https://www.ncbi.nlm.nih.gov/pubmed/27300467
http://dx.doi.org/10.1002/anie.201603399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094546/
https://www.ncbi.nlm.nih.gov/pubmed/27300467
http://dx.doi.org/10.1002/anie.201603399

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