Tau physiology and pathomechanisms in frontotemporal lobar degeneration

Frontotemporal lobar degeneration (FTLD) has been associated with toxic intracellular aggregates of hyperphosphorylated tau (FTLD‐tau). Moreover, genetic studies identified mutations in the MAPT gene encoding tau in familial cases of the disease. In this review, we cover a range of aspects of tau fu...

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Detalles Bibliográficos
Autores principales: Bodea, Liviu‐Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier, Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Frontotemporal dementias: From molecular mechanisms to therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094566/
https://www.ncbi.nlm.nih.gov/pubmed/27306859
http://dx.doi.org/10.1111/jnc.13600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094566/
https://www.ncbi.nlm.nih.gov/pubmed/27306859
http://dx.doi.org/10.1111/jnc.13600

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