The Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost Minimization

Bacterial growth depends crucially on metabolic fluxes, which are limited by the cell’s capacity to maintain metabolic enzymes. The necessary enzyme amount per unit flux is a major determinant of metabolic strategies both in evolution and bioengineering. It depends on enzyme parameters (such as k(ca...

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Detalles Bibliográficos
Autores principales: Noor, Elad, Flamholz, Avi, Bar-Even, Arren, Davidi, Dan, Milo, Ron, Liebermeister, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094713/
https://www.ncbi.nlm.nih.gov/pubmed/27812109
http://dx.doi.org/10.1371/journal.pcbi.1005167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094713/
https://www.ncbi.nlm.nih.gov/pubmed/27812109
http://dx.doi.org/10.1371/journal.pcbi.1005167

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